Chapter 1 Introduction

Welcome to LATINART: Landmark Trials In Nephrology And Renal Transplant. This is an attempt to list the landmark trials in nephrology and renal transplant.

1.1 Types of study

Studies are categorised as follows:

• = randomised controlled trial
  
• = meta-analysis of RCTs
  
• = observational study
  
• = physiological study (or other)

Truly landmark studies (one or two only in each chapter) are marked with stars: .

1.2 Other lists of ‘landmark’ trials

This is a subjective list. A more objective catalogue can be found in the 100 most-cited articles in nephrology.

It is also worth looking at the NephJC / RFN “top 10 stories” of…

• 2021
• 2020
• 2019
  
• 2018
  
• 2017
  
• 2016

(…and the article for 2016 has links for every year going back to 2010.)

1.3 Going deeper

This is merely a list. It is NOT an attempt to interpret or discuss the trials in any depth. There are several excellent open-access resources for this such as:

• NephJC
  
• uKidney
  
• Landmark nephrology
  
• Visualmed
  
• 2minutemedicine

1.4 Recent trials: see Twitter feed

The renalRCTs twitter feed posts most new publications of RCTs in renal and transplant medicine. Papers of particular interest are flagged as “liked”:

this Twitter timeline

.